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ademtech company
History

Created in 2000, ADEMTECH SA, a company based in PESSAC (Gironde) and initially owing a large know-how in Emulsion technology has developed and produced superparamagnetic nanoparticles for in vitro diagnostic and life sciences.

The association of complementary skills such as physicochemistry, polymer chemistry, immunology, cellular biology, molecular biology and virology leads to the development of novel nano-objects with unique characteristics.

Ademtech manufactures calibrated particles (CV<20%) of 100 to 500 nm, with high magnetic content (70% of iron oxides) and controlled surface bearing various functionalities – carboxylic acids and amine – and biological activities brought by streptavidine, antibodies or proteins A and G.

These magnetic particles are especially designed for concentration, separation, purification and identification of molecules and specific cells. Besides, they are particularly suitable for integration in microfluidic devices.

Ademtech offers its core expertise to customised coupling services based on the nano particules in order to develop specific purification tools.

For the near future, ADEMTECH is developing some diagnostic and scientific research applications offering a global solution to the costumers including devices and instruments.
Technology
A proprietary technology guarantees a reproductible manufacturing process of calibrated magnetic emulsions. The fragmentation under controlled shearing allows for the preparation of 100 to 500 nm uniform magnetic emulsions (see figure below).

calibrated magnetic emulsion magnetic emulsion
The nanoparticles are superparamagnetic : they exhibit magnetic properties only when placed within a magnetic field and show no residual magnetism when removed from this field.

magnetic particles
Self-organisation of magnetic particles occurs when stimulated by a magnetic field. Separation is gentle and no column or centrifugations are necessary.
Ademtech has developed in-house polymerisation process ensuring an efficient isolation of the magnetic core, a tuneable functionalisation and a high colloidal stability.

polymerised magnetic particles

The polymer provides the magnetic core with a uniform protective shell in order to isolate iron oxides that can interfere with some enzymatic reactions (as shown on Transmission Electron Microscopy photos).

The hydrophilic surface lowers non-specific interactions with proteins.
The high magnetic content (more than 70%) ensures a quick and gentle magnetic separation even for the smallest particles with a simple magnet.
Ademtech has developed simple and reproductible protocols for coupling proteins to its nanoparticles yielding to high binding capacities while keeping non-specific binding low and ensuring long-term stability.
Finance / Investor Relations

Up to now, Ademtech has raised approx € 2 million. The second round of financing, which closed in December 2004, was led by Bioam together with regional investors Expanso Capital, SOCRI and Aquitaine Création Innovation, and private shareholders.

Bioam
With a subscribed capital of € 51 million, Bioam is a venture capital fund dedicated to early-stage financing of companies involved in biotechnology and its applications in the healthcare, agrifood and environment industries.

fonds Bioam
Biogestion - Fonds Bioam
12, rue La Boétie
F-75008 PARIS
Phone : +33 (0)1 58 18 60 70
Fax : +33 (0)1 58 18 60 78
www.bioam.fr

Galia Gestion
Galia Gestion invests in innovative early-stage companies established in Aquitaine and Midi-Pyrénées Regions. Expanso Capital is a venture capital fund managed by Galia Gestion.

galia gestion
Galia Gestion
2, rue des Piliers de Tutelle BP 149
F-33025 BORDEAUX Cedex
Phone : +33 (0)5 57 81 88 10
Fax : +33 (0)5 56 52 17 34
www.galia-gestion.com

SOCRI
Sud-Ouest Capital Risque Innovation is a venture capital fund dedicated to innovative companies established in Aquitaine and Midi-Pyrénées Regions. Interventions are realized by co-investments with others regional investors.
SOCRI
18, place Dupuy BP 808
F-31080 TOULOUSE Cedex 6
Phone : +33 (0)5 34 41 74 17
Fax : +33 (0)5 34 41 74 19
ACI
Aquitaine Création investissement is a regional venture capital fund dedicated to creation or innovation projects.

aquitaine creation investissement
ACI
Centre Condorcet
162, avenue A. Schweitzer
F-33600 PESSAC
Phone : +33 (0)5 56 15 11 90
Fax : +33 (0)5 56 15 11 97
www.aquitaine-creation.com
ISO 9001:2008 Certification
iso 9001
Our Product development, Manufacture, Marketing and Sales Departments have been awarded certification under the International Standard ISO 9001 version 2008 since February 2003.

This certification requires a company to demonstrate its ability to consistently provide products and services that meet the needs of its customers and to continually improve its quality management system.

Careers

We are seeking talented and motivated individuals to join our dynamic team in helping develop tools that advance life sciences research.

To apply for a position, please forward your resume to :

ADEMTECH
Parc Scientifique Unitec 1
4, allée du doyen Georges Brus
F-33600 PESSAC
ADEMTECH Parc Scientifique Unitec 1, 4 Allée du Doyen Georges Brus 33600 Pessac-France Ph:+33 (0)557 020 200 Fax: +33 (0)557 020 206